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KMID : 0358419950380081419
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Korean Journal of Obstetrics and Gynecology
1995 Volume.38 No. 8 p.1419 ~ p.1424
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The Evaluation of Gestational Sac Growth in Ovulation-Induced Singleton Pregnancies
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김정구
김석현/최영민/신창재/문신용/장윤석/이진용
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Abstract
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The purpose of this study is to evaluate if gestational sac (GS) growth in ovulation-induced pregnancies may be different from that in spontaneously occurring pregnancies. The GS diameter and volume were measured by transvaginal ultraonography at
6
to 8
weeks of gestation in 62 sigleton pregnancies induced by clomiphene citrate(CC)/human chorionic gonadotropin (hCG) (n=18), human menopausal gonadotropin(hMG)/hCG(n=30) and gonadotropin releasing hormone agonist (GnRHa)/follicle stimulating
hormone(FSH)/hCG(n=14) and in 32 normal pregnancies occurred spontaneously after tubal reanastomosis as controls. All pregnancies subsequently ended in a delivery of normal term healthy infant. The mean GS diameter in control pregnancies at 6 to
8
weeks
of gestation was 17.76±1.13mm, 23.06±1.18mm, 32.75±1.19mm and the mean GS volume 3.91±0.65ml, 9.01±1.29ml, 20.17±2.10ml. The mean GS diameter and GS volume were reduced significantly (P<0.02) at 6 weeks in CC/hCG-induced pregnancies, at 6
and
8weeks I hMG/hCG-induced pregnancies, at 6 to 8 weeks in GnRHa/FSH/hCG -induced pregnancies, compared with those in control pregnancies. The mean GS diameter and GS volume in GnRHa/FSH/hCG-induced pregnancies were significantly (P<0.02) lower
than
those
in other ovulation-induced pregnancies at 6 and 7 weeks. These data suggest that early growth development in ovulation-induced pregnancies is delayed and that early pregnancy physiology in these pregnancies may be different from naturally
occurring
pregnancies.
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KEYWORD
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